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Beyond the MNA: A Biological Vulnerability Phenotype Associated with Prolonged Hospitalization in Older Adults.

Nutrients - 11 Feb 2026

Boccardi Virginia, Mancinetti Francesca, Balducci Cesare, Labbozzetta Valeria, Ercolanetti Elena, Ruggiero Carmelinda, Ercolani Sara, Mecocci Patrizia

Abstract excerpt

BACKGROUND/OBJECTIVES: Nutritional status in hospitalized older adults is usually evaluated using screening tools such as the Mini Nutritional Assessment (MNA). During acute illness, however, these tools may overlook biologically relevant vulnerability related to inflammation and metabolic stress, a condition often described as occult malnutrition. The clinical implications of applying a more stringent biological...

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PMID: 41754103
DOI: 10.3390/nu18040586
PMCID: PMC12943111

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