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Comparative evaluation of SNP sequencing workflows for identification of the missing in Vietnam.

Forensic science international. Genetics - 1 Jun 2026

Forsythe Bethany K, van Haperen Bas, Vangeel Lisa, Hill Kieren J, Bastisch Ingo, Do Phong H, Hoang Thuy T, Johnson Lucy, Le Dung T, Nguyen Nam N, Nguyen Chau, Tran Linh H, Tran Vinh V, Vu Tuan A, Chu Ha H, Hoang Ha, Tran Thanh T, Parsons Thomas J

Abstract excerpt

Hundreds of thousands of remains are still unidentified following the 1955-1975 conflict in Vietnam. DNA identification is increasingly challenging due to extreme degradation of remaining DNA, a large amount of contaminating microbial DNA, and a growing reliance on distant relatives to provide reference samples for comparison. Although mitochondrial DNA is easier to recover than nuclear DNA, by itself it does not...

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PMID: 41734637
DOI: 10.1016/j.fsigen.2026.103448

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