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Article

Sensitive Detection of Gynecological Cancer Recurrence Using Circulating Tumor DNA and Digital PCR: A Comparative Study with Serum Biochemical Markers.

International journal of molecular sciences - 8 Nov 2024

Balasan Nour, Kharrat Feras, Di Lorenzo Giovanni, Athanasakis Emmanouil, Bianco Anna Monica, Conti Andrea, Di Stazio Maria Teresa, Butera Giulia, Cicogna Stefania, Mangogna Alessandro, Romano Federico, Ricci Giuseppe, d'Adamo Adamo Pio

Abstract excerpt

Early detection of recurrences in gynecological cancers is crucial for women's health. Circulating tumor DNA (ctDNA) analysis through liquid biopsy offers a promising approach for monitoring disease progression and identifying relapses. This study investigated the utility of digital Polymerase Chain Reaction (dPCR) for ctDNA detection in three gynecological cancer patients with clinically confirmed relapses...

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Aged
Biomarkers, Tumor
Circulating Tumor DNA
Genital Neoplasms, Female

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Neoplasm Recurrence, Local

Polymerase Chain Reaction

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Open in PubMed Open full text

Identifiers

PMID: 39596073
DOI: 10.3390/ijms252211997
PMCID: PMC11593349

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 1 Sept 2026.

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