Article
Joint modeling of whole-genome sequencing data for human height via approximate message passing.
Cell genomics - 13 May 2026
Depope Al, Bajzik Jakub, Mondelli Marco, Robinson Matthew R
Abstract excerpt
Human height is a model for the genetic analysis of complex traits, and recent studies suggest the presence of thousands of common genetic variant associations and hundreds of low-frequency/rare variants. Here, we develop a new algorithmic paradigm based on approximate message passing (genomic vector approximate message passing [gVAMP]) for identifying DNA sequence variants associated with complex traits and...
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