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Article

Will Big Data Close the Missing Heritability Gap?

Genetics - 1 Nov 2017

Kim Hwasoon, Grueneberg Alexander, Vazquez Ana I, Hsu Stephen, de Los Campos Gustavo

Abstract excerpt

Despite the important discoveries reported by genome-wide association (GWA) studies, for most traits and diseases the prediction R-squared (R-sq.) achieved with genetic scores remains considerably lower than the trait heritability. Modern biobanks will soon deliver unprecedentedly large biomedical data sets: Will the advent of big data close the gap between the trait heritability and the proportion of variance...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

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Identifiers

PMID: 28893854
DOI: 10.1534/genetics.117.300271
PMCID: PMC5676235

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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