Article
[Elucidating the gene-environment interplay in risk factors for Age-related hearing loss].
Lin chuang er bi yan hou tou jing wai ke za zhi = Journal of clinical otorhinolaryngology head and neck surgery - 1 Mar 2026
Zan Hongyuan, Li Jiayu, Zhang Ren, Yang Jingwen, Wang Hui
Abstract excerpt
Objective:To investigate the associations of genetic factors, environmental exposures, and their interactions with the risk of age-related hearing loss(ARHL). Methods:This case-control study utilized data from the UK Biobank and meta-analyses. Multivariable logistic regression models were employed to analyze the main effects of environmental exposures. A polygenic risk score(PRS) was constructed to assess genetic...
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