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Article

RCBVmax from DSC Perfusion MRI as a Supportive Imaging Biomarker for Differentiating IDH-Mutant Astrocytomas and Oligodendroglioma.

Clinical neuroradiology - 1 Jun 2026

Mannil Manoj, Rubbert Christian, Musigmann Manfred, Prokop Mathias, Feraco Paola, Meijer Frederick J A, Smits Marion, Van der Kolk Anja G, Henssen Dylan

Abstract excerpt

BACKGROUND: Gliomas, particularly astrocytomas (IDH-mutated, 1p/19q intact) and oligodendrogliomas (IDH-mutated, 1p/19q co-deleted), differ significantly in their clinical behavior and prognosis. Accurate differentiation between these subtypes is crucial for guiding therapeutic decisions. Non-invasive imaging biomarkers, such as T2-Flair mismatch sign and relative cerebral blood volume (rCBV), have shown promise...

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Identifiers

PMID: 41706138
DOI: 10.1007/s00062-026-01624-w
PMCID: PMC13319155

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