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Article

Investigating glioma genetics through perfusion MRI: rCBV and rCBF as predictive biomarkers.

Magnetic resonance imaging - 1 Apr 2025

Śledzińska-Bebyn Paulina, Furtak Jacek, Bebyn Marek, Bartoszewska-Kubiak Alicja, Serafin Zbigniew

Abstract excerpt

BACKGROUND: Brain tumors exhibit diverse genetic landscapes and hemodynamic properties, influencing diagnosis and treatment outcomes. PURPOSE: To explore the relationship between MRI perfusion metrics (rCBV, rCBF), genetic markers, and contrast enhancement patterns in gliomas, aiming to enhance diagnostic accuracy and inform personalized therapeutic strategies. Additionally, other radiological features, such as...

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Topics

Adult
Aged
Female
Humans
Male
Middle Aged
Young Adult

Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

Biomarkers, Tumor

Brain

Brain Neoplasms

Cerebrovascular Circulation

Contrast Media

Glioma

Magnetic Resonance Angiography

Mutation

Perfusion Magnetic Resonance Imaging

Retrospective Studies

Sensitivity and Specificity

Source

Identifiers

PMID: 39740747
DOI: 10.1016/j.mri.2024.110318

Genes

CDKN2A
IDH1
EGFR
PDGFRA
MGMT
PTEN
TERT
TP53

Provenance

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