Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Comparative analysis of draper mutant alleles and RNAi expression systems in the ovary and brain of Drosophila melanogaster.

G3 (Bethesda, Md.) - 6 May 2026

Liu Guangmei, Yang Pamela, Le Trung, Shin Jerald, Shi Cheng Yang, Budhram Emily, McCall Kimberly

Abstract excerpt

The phagocytic receptor Draper (Drpr) mediates clearance of apoptotic cells in Drosophila melanogaster, yet how distinct drpr alleles and RNAi constructs differ in efficiency and phenotypic outcomes has not been systematically compared. Here, we evaluate multiple drprRNAi lines across UAS/GAL4, QUAS/QF2, and LexA/LexAop systems, alongside a newly generated CRISPR allele (drprCR1). Immunostaining confirmed...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Alleles
Share to Brain
Share to Drosophila melanogaster

Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

Share to Drosophila Proteins

Share to Gene Knockdown Techniques

Share to Membrane Proteins

Share to RNA Interference

Source

Open in PubMed Open full text

Identifiers

PMID: 41699780
DOI: 10.1093/g3journal/jkag040
PMCID: PMC13148388

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 9 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Comparative analysis of draper mutant alleles and RNAi expression systems in the ovary and brain of Drosophila melanogaster.PMID 41699780Read ↗

Neuronal regulated Ire1-dependent mRNA decay controls germline differentiation in <i>C. elegans</i>Semantic proximity Read ↗

A genomewide RNAi screen for genes that affect the stability, distribution and function of P granules in Caenorhabditis elegans.Semantic proximity Read ↗

Insights into dentatorubral-pallidoluysian atrophy from a new Drosophila model of diseaseSemantic proximity Read ↗

ELLI-1, a novel germline protein, modulates RNAi activity and P-granule accumulation in Caenorhabditis elegans.Semantic proximity Read ↗

Multi-modal comparison of molecular programs driving nurse cell death and clearance in Drosophila melanogaster oogenesisSemantic proximity Read ↗

Endogenous Expression and Subcellular Localization of Core Apoptosis Regulators Reveal Key Differences Between Embryonic and Germline Apoptosis in C. elegansSemantic proximity Read ↗

Natural genetic variation screen in <i>Drosophila</i> identifies Wnt signaling, mitochondrial metabolism, and redox homeostasis genes as modifiers of apoptosisSemantic proximity Read ↗

Multi-modal comparison of molecular programs driving nurse cell death and clearance in <i>Drosophila melanogaster</i> oogenesisSemantic proximity Read ↗

Biphasic Subcellular Localization of the DAZL-Related Protein Boule inDrosophilaSpermatogenesisSemantic proximity Read ↗

Mutations in the novel membrane protein spinster interfere with programmed cell death and cause neural degeneration in Drosophila melanogaster.Semantic proximity Read ↗

Generation and Characterization of Germline-Specific Autophagy and Mitochondrial Reactive Oxygen Species Reporters in DrosophilaSemantic proximity Read ↗

EOR-1/PLZF-regulated WAH-1/AIF sequentially promotes early and late stages of non-apoptotic corpse removalSemantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.