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Article

Mitochondrial heterogeneity in a patient with preeclampsia.

Free radical biology & medicine - 1 Apr 2026

Rajasekaran Vasanthi, Dubey Shubham, Kaushik Teshi, Neuenschwander Annalese G, Rajasekaran Namakkal-Soorappan, Berkowitz Dan E, Dubey Praveen K

Abstract excerpt

Preeclampsia (PE) is a pregnancy disorder characterized by high blood pressure and proteinuria after the 20th week. In this condition, reduced blood flow to the placenta leads to placental ischemia and oxidative stress, resulting in mitochondrial DNA damage and dysfunction. In this case of preeclampsia, a unique feature is observed: the presence of mitochondrial heterogeneity and heteroplasmy in the preeclamptic...

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Identifiers

PMID: 41687748
DOI: 10.1016/j.freeradbiomed.2026.02.025

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026.

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