Article
Global prevalence of Duchenne and Becker muscular dystrophy: a systematic review and meta-analysis.
Journal of orthopaedic surgery and research - 15 Feb 2022
Salari Nader, Fatahi Behnaz, Valipour Elahe, Kazeminia Mohsen, Fatahian Reza, Kiaei Aliakbar, Shohaimi Shamarina, Mohammadi Masoud
Abstract excerpt
BACKGROUND: A variety of mutations in the largest human gene, dystrophin, cause a spectrum from mild to severe dystrophin-associated muscular dystrophies. Duchenne (DMD) and Becker (BMD) muscular dystrophies are located at the severe end of the spectrum that primarily affects skeletal muscle. Progressive muscle weakness in these purely genetic disorders encourages families with a positive history for genetic...
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