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Article

FokI vitamin D receptor polymorphism as a protective factor in intrahepatic cholestasis of pregnancy.

Ginekologia polska - 1 Jan 2000

Wolski Hubert, Kurzawinska Grazyna, Ozarowski Marcin, Drews Krzysztof, Barlik Magdalena, Piatek Krzysztof, Malewski Zbyszko, Mrozikiewicz Aleksandra E, Magielda-Stola Justyna, Kolanowska Dorota, Wolek Marlena, Seremak-Mrozikiewicz Agnieszka

Abstract excerpt

OBJECTIVES: Intrahepatic cholestasis in pregnancy (ICP) is a pregnancy-specific liver disorder. Its etiology is not fully understood. Increasing evidence indicates the important role of vitamin D and the vitamin D receptor (VDR) in this disorder. The presence of polymorphic variants in the VDR gene could influence its activity and susceptibility to ICP development. The goal of the study was to investigate the...

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Identifiers

PMID: 33447990
DOI: 10.5603/GP.a2020.0135

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