Article
Mid-esophageal mucosal impedance reflects mucosal integrity and phenotypes refractory reflux-like symptoms.
BMC gastroenterology - 9 Feb 2026
Li Bo, Chen Ye, Chen Ying, Wang Zhenxiang, Zhang Yan, Sun Huihui, Xu Shuchang
Abstract excerpt
BACKGROUND: Refractory reflux-like symptoms (rRLS) are frequently encountered in clinical practice and often reflect heterogeneous underlying mechanisms beyond acid exposure alone. Esophageal mucosal impedance has emerged as a marker of mucosal integrity, yet its role in phenotyping rRLS remains incompletely defined. METHODS: In this retrospective study, adult patients with reflux-like symptoms who underwent...
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