Article
Identification of Different Phenotypes of Esophageal Reflux Hypersensitivity and Implications for Treatment.
Clinical gastroenterology and hepatology : the official clinical practice journal of the American Gastroenterological Association - 1 Apr 2021
Sawada Akinari, Guzman Mauricio, Nikaki Kornilia, Sonmez Shirley, Yazaki Etsuro, Aziz Qasim, Woodland Philip, Rogers Benjamin, Gyawali C Prakash, Sifrim Daniel
Abstract excerpt
BACKGROUND & AIMS: Reflux hypersensitivity (RH), a functional esophageal disorder, is detected in 14%-20% of patients who present with typical esophageal symptoms. As many as 40% of patients with RH do not respond to treatment with pain modulators or proton pump inhibitors (PPIs); behavior disorders might contribute to lack of treatment efficacy. We aimed to assess the prevalence of behavioral disorders and their...
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