Article
Rate variation and recurrent sequence errors in pandemic-scale phylogenetics.
Nature methods - 1 Mar 2026
De Maio Nicola, Willemsen Myrthe, Martin Samuel, Guo Zihao, Saha Abhratanu, Hunt Martin, Ly-Trong Nhan, Minh Bui Quang, Iqbal Zamin, Goldman Nick
Abstract excerpt
Phylogenetic analyses of genome sequences from infectious pathogens reveal essential information regarding their evolution and transmission, as seen during the coronavirus disease 2019 pandemic. Recently developed pandemic-scale phylogenetic inference methods reduce the computational demand of phylogenetic reconstruction from genomic epidemiological datasets, allowing the analysis of millions of closely related...
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