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Article

Genetic associations of LXN polymorphisms with toxicities of platinum-based concurrent chemoradiotherapy of nasopharyngeal carcinoma.

Supportive care in cancer : official journal of the Multinational Association of Supportive Care in Cancer - 5 Feb 2026

Wang Youhong, Ma Siqing, Bao Jiancheng, Zhang Zehong, Song Jiachun, Tai Yu, Gao Yingting, Feng Wei, An Liang

Abstract excerpt

PURPOSE: Oral mucositis (OM) is a common and debilitating adverse effect associated with chemoradiotherapy in nasopharyngeal carcinoma. This study aimed to investigate the association between Latexin (LXN) polymorphism and acute toxicity of oral mucositis. METHODS: A total of 238 nasopharyngeal carcinoma (NPC) patients were enrolled. LXN genotypes were analyzed by the Sequenom MassARRAY system. Multivariate...

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Identifiers

PMID: 41642350
DOI: 10.1007/s00520-026-10378-7
PMCID: PMC12876459

Genes

LXN

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026.

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