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Genomic comparison and phenotypic characterization of Pseudomonas aeruginosa isolates across environmental and diverse clinical isolation sites.

mSystems - 24 Mar 2026

Penaranda Cristina, Brenner Evan P, Clatworthy Anne E, Cosimi Lisa A, Ravi Janani, Hung Deborah T

Abstract excerpt

Pseudomonas aeruginosa is a clinically significant, opportunistic pathogen adept at thriving in both host-associated and environmental settings. We sought to define the extent to which P. aeruginosa isolates specialize across niches using a comprehensive study of whole-genome sequencing with paired phenotypic characterization of 125 P. aeruginosa isolates from diverse clinical and environmental sites. We...

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Identifiers

PMID: 41641989
DOI: 10.1128/msystems.01362-25
PMCID: PMC13011455

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