Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Sex and APOE ε4 genotype modify risk factor associations with cerebral amyloid angiopathy: a multi-cohort autopsy study.

Alzheimer's research & therapy - 4 Feb 2026

Ma Liwei, Wang Yihan, Goudey Benjamin, Jin Liang, Pan Yijun

Abstract excerpt

BACKGROUND: This study aimed to identify risk factors and develop statistical models to predict cerebral amyloid angiopathy (CAA). METHODS: Associations between demographic, cognition, cardiovascular, and AD-related neuropathology and CAA were analyzed using data from three longitudinal cohorts of aging and dementia. Logistic regression with LASSO was used for feature selection. Predictive performance was...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Apolipoprotein E4
Share to Autopsy
Share to Brain

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Cerebral Amyloid Angiopathy

Share to Cohort Studies

Share to Longitudinal Studies

Share to Memory, Episodic

Share to Sex Factors

Source

Open in PubMed Open full text

Identifiers

PMID: 41639906
DOI: 10.1186/s13195-025-01948-8
PMCID: PMC12964862

Genes

APOE

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Sex and APOE ε4 genotype modify risk factor associations with cerebral amyloid angiopathy: a multi-cohort autopsy study.PMID 41639906Read ↗

Clinical predictors of severe cerebral amyloid angiopathy and influence of APOE genotype in persons with pathologically verified Alzheimer disease.Semantic proximity Read ↗

Factors associated with intracerebral hemorrhage in confirmed cerebral amyloid angiopathy.Semantic proximity Read ↗

Cerebral amyloid angiopathy and its co-occurrence with Alzheimer's disease and other cerebrovascular neuropathologic changes.Semantic proximity Read ↗

Data Analysis With Shapley Values For Automatic Subject Selection in Alzheimer's Disease Data Sets Using Interpretable Machine LearningSemantic proximity Read ↗

Cerebral amyloid angiopathy and Alzheimer's and related pathologies across APOE genotypes.Semantic proximity Read ↗

APOE and cerebral amyloid angiopathy in community-dwelling older persons.Semantic proximity Read ↗

Cerebral Amyloid Angiopathy Burden and Cerebral Microbleeds: Pathological Evidence for Distinct Phenotypes.Semantic proximity Read ↗

MCH-Guard: Multimodal Machine Learning Framework for Risk Stratification of Cerebral Microhemorrhage Risk in the Alzheimer’s Disease Neuroimaging InitiativeSemantic proximity Read ↗

Discovering the Italian phenotype of cerebral amyloid angiopathy (CAA): the SENECA project.Semantic proximity Read ↗

Alzheimer’s disease and neurodegeneration in symptomatic cerebral small vessel diseaseSemantic proximity Read ↗

Blood-brain barrier dysfunction in cerebral amyloid angiopathy is associated with disseminated cortical superficial siderosisSemantic proximity Read ↗

Neuropathological Correlates of Apathy Progression in Alzheimer’s Disease and Related Dementias: A Longitudinal NACC Cohort StudySemantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.