Article
cagA-positive Helicobacter pylori and human NOS2-954G/C polymorphism: A possible association with severe clinical outcomes in Iranian patients.
Infection, genetics and evolution : journal of molecular epidemiology and evolutionary genetics in infectious diseases - 1 Mar 2026
Rezaeian Tayebeh, Mohammadzadeh Roghayeh, Akbari Shadi, Namdar Ali Beheshti, Baghaee Bita, Ahmadi Ayat, Farsiani Hadi
Abstract excerpt
Helicobacter pylori infects more than 50% of the global population. The diversity and severity of clinical outcomes are attributed to the complex interaction among pathogen, host, and environmental factors. This study investigated the association between H. pylori virulence genes (cagA, vacA, and dupA) and human host NOS2-954G/C polymorphism with clinical outcomes in H. pylori-infected Iranian patients....
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