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Article

SHED-exosomes functionalized micro-nano bioactive glass/PCL membrane regulates macrophage polarization and promotes osteogenic differentiation.

Journal of applied oral science : revista FOB - 1 Jan 2026

Yan Yongyong, Lan Haifeng, Miao Guohou, Wang Haiyan, Li Zhengmao, Zhang Qing, Wang Shuai, Wu Gang, Jaspers Richard T, Pathak Janak L

Abstract excerpt

Micro-nano bioactive glass (MNBG) has bone regenerative potential. However, the difficulty of MNBG molding restricts its clinical applications in bone regeneration. Exosomes carry proteins, lipids, and nucleic acids for communication between cells. In this study, we adhered human exfoliated deciduous teeth (SHED)-derived exosomes (SHED-Exos) to electrospun micro-nano bioactive glass/polycaprolactone (MNBG/PCL)...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Identifiers

PMID: 41637337
DOI: 10.1590/1678-7765-2025-0541
PMCID: PMC13123774

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026.

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