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Article

The Correlation Among PD-L1 Expression and the Driver Genes Status in Malignant Pleural Effusion of Lung Adenocarcinoma.

Cytopathology : official journal of the British Society for Clinical Cytology - 1 Jul 2026

Wang Rui, Ma Yang, Liu Ying, Wu Juan, Guo Xiao, Du Yun

Abstract excerpt

BACKGROUND: The objective of this study was to investigate the protein expression of PD-L1 in the pleural fluid of lung adenocarcinoma patients with malignant pleural effusion. Additionally, we aimed to analyse the association between PD-L1 expression and the mutational status of ten driver genes: EGFR, ALK, ROS1, BRAF, KRAS, NRAS, HER2, RET, PIK3CA, and MET. METHODS: A total of 161 cytological specimens were...

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Source

Identifiers

PMID: 41636388
DOI: 10.1111/cyt.70052

Genes

ALK
BRAF
KRAS
EGFR
MET
ROS1
NRAS
PIK3CA
RET

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026.

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