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Article

The Role of CCR1 as a decisive factor for immune response activation versus suppression phenotypes in gastric cancer.

Neoplasia (New York, N.Y.) - 1 Mar 2026

Sun Keran, Ning Jingyuan, Jia Keqi, Fan Xiaoqing, Li Hongru, Ma Cuiqing, Wei Lin

Abstract excerpt

BACKGROUND: Chemokine receptor 1 (CCR1), a regulator of immune cell migration, has been implicated in various cancers but remains poorly characterized in gastric cancer's immune microenvironment. This study aimed to investigate whether CCR1 promotes or suppresses tumor progression in gastric cancer. METHODS: Utilize transcriptomic analysis to investigate the role of CCR1 in gastric cancer, and employed clinical...

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Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

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Source

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Identifiers

PMID: 41621162
DOI: 10.1016/j.neo.2026.101277
PMCID: PMC12886516

Genes

CCR1
CXCL10
CXCL9
CD68

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 23 Oct 2026.

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