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Article

Causal association between multiple sclerosis and trigeminal neuralgia: A Mendelian randomization study with meta-analysis.

Cranio : the journal of craniomandibular practice - 1 Sept 2026

Halboub Esam, Al-Jamaei Aisha A, Al-Amir Abdulwahab, Al-Soneidar Walid A, Al-Maweri Sadeq Ali, Al-Mekhlafi Hesham M, Alhajj Mohammed Nasser

Abstract excerpt

OBJECTIVE: This study utilized a meta-analysis of two-sample Mendelian randomization (MR) to investigate the causal link between multiple sclerosis (MS) and trigeminal neuralgia (TN). METHODS: Using genetic summary data from the OpenGWAS database (European descent), researchers identified eight MS GWAS studies as exposures and one TN study as the outcome. Ten MR approaches, including IVW and MR-Egger, were...

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PMID: 41604238
DOI: 10.1080/08869634.2026.2619521

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 8 Sept 2026.

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