Article
Examination of In Vivo Mutations in VP4 (VP8*) of the Rotarix® Vaccine from Shedding of Children Living in the Amazon Region.
Viruses - 3 Jan 2026
Silva Mauro França, Silva Beatriz Vieira da, Ramalho Emanuelle, Pimenta Yan Cardoso, Silva Leonardo Luiz Pimenta da, Vieira Laricy da Silva, Xavier Maria da Penha Trindade Pinheiro, Olivares Alberto Ignacio Olivares, Leite José Paulo Gagliardi, Moraes Marcia Terezinha Baroni de
Abstract excerpt
Group A rotaviruses (RVAs) remain the leading cause of acute gastroenteritis (AGE) in young children in low- and middle-income countries. In Brazil, the oral attenuated RVA vaccine (Rotarix®), monovalent genotype G1P[8], is distributed by the national immunization program and has drastically reduced morbidity and mortality associated with RVA etiology. In this study, Rotarix® G1P[8] was detected using specific...
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