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Article

Who Am I? Eyebrow Follicles Minimize Donor-Derived DNA for Germline Testing After Hematopoietic Stem Cell Transplantation.

International journal of molecular sciences - 12 Jan 2026

Mertens Matthias, Sadlo Mona, Kühl Jörn-Sven, Metzeler Klaus, Zschenderlein Louisa, Edelmann Jeanett, Lehmann Claudia, Thull Sarah, Karakaya Mert, Velmans Clara, Tumewu Theresa, Böhme Matthias, Klötzer Christina, Weigert Anne, Vucinic Vladan, Hentschel Julia, Mertens Mareike

Abstract excerpt

Germline genetic testing plays a critical role in diagnosing inherited predispositions and increasingly guides therapeutic and surveillance choices-but becomes technically challenging after allogeneic hematopoietic stem cell transplantation (HSCT), when donor-derived DNA contaminates host tissues. To address this, we compared donor-derived DNA across three accessible tissues-buccal swab, nail, and eyebrow...

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DNA
Genetic Testing
Germ Cells
Hematopoietic Stem Cell Transplantation

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

High-Throughput Nucleotide Sequencing

Microsatellite Repeats

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Identifiers

PMID: 41596394
DOI: 10.3390/ijms27020744
PMCID: PMC12841102

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 1 Sept 2026.

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