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Article

Recommendations for (Pharmaco)Genetic Sampling in Patients Following Allogeneic Hematopoietic Stem Cell Transplantation.

Clinical and translational science - 1 Aug 2025

Bokma Anniek, Matic Maja, Ralf Arwin, van den Bosch Bianca J C, Kayser Manfred, van Schaik Ron H N, Lafeber Melvin, Coenen Marieke J H, Atrafi Florence

Abstract excerpt

In patients receiving allogenic hematopoietic stem cell transplantation (aHSCT) complete chimerism is desired. However, this brings a challenge when non-invasive assessment of recipient germline DNA is required for genetic testing. Here, we aim to create awareness for (pharmaco)genetic sampling in patients following aHSCT based on a case report of a patient following aHSCT in which pharmacogenetic analysis was...

Topics

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CYP2C19 gene
CYP2C9 gene
CYP3A4 gene
VKORC1 gene
Genotype

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Hematopoietic Stem Cell Transplantation

Pharmacogenomic Testing

Transplantation, Homologous

Source

Open in PubMed Open full text

Identifiers

PMID: 40802525
DOI: 10.1111/cts.70303
PMCID: PMC12345918

Genes

SLCO1B1
CYP2C19
CYP2C9
CYP3A4
VKORC1

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 1 Sept 2026.

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