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Article

KRAS mutations reshape the immunosuppressive tumor microenvironment in triple-negative breast cancer: A novel perspective.

Critical reviews in oncology/hematology - 1 Mar 2026

Lv Yuanhao, Zhao Ziyin, Di Wenyu, Liu Lei, Chen Yiyang, Su Wei, Ji Yinghua, Zhong Jiateng

Abstract excerpt

Triple-negative breast cancer (TNBC) is an aggressive subtype characterized by poor prognosis and limited therapeutic options due to the lack of well-defined molecular targets. While conventional studies have primarily focused on tumor cell-intrinsic oncogenic mechanisms, this article presents a novel perspective emphasizing the pivotal role of KRAS mutations in remodeling the tumor microenvironment (TME) of...

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Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

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Identifiers

PMID: 41581736
DOI: 10.1016/j.critrevonc.2026.105150

Genes

KRAS

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 8 Sept 2026.

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