Article
Mendelian randomization study on the causal effects of omega-3 fatty acids on rheumatoid arthritis.
Clinical rheumatology - 1 May 2022
Zhu Gaizhi, Zhou Shan, Xu Yaqi, Gao Ran, Li Huan, Zhai Bing, Liu Xiaoling, He Youdi, Wang Xiaoqian, Han Gencheng, Su Wenting, Wang Renxi
Abstract excerpt
OBJECTIVES: To resolve the ongoing debate on the role of plasma omega-3 fatty acids in rheumatoid arthritis (RA), we attempted to identify the association between omega-3 intake and the risk of RA. METHODS: We analyzed data from the largest genome-wide association study (GWAS) for omega-3 fatty acids (N = 114,999 of European ancestry) and RA (14,361 cases and 43,923 controls of European ancestry). Mendelian...
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