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Article

Emerging multi-omics biomarkers in glioblastoma: Integrative insights from genomics to metabolomics.

Biochimica et biophysica acta. Reviews on cancer - 1 Apr 2026

Kakde Ganesh S, Dakal Tikam Chand, Maurya Pawan Kumar

Abstract excerpt

Glioblastoma (GBM) is the most malignant form of primary brain tumor in adults, described by profound molecular heterogeneity, rapid progression, and limited therapeutic response. Despite advances in chemotherapy (TMZ), radiotherapy, and surgery, patient outcomes remain poor, with a median survival of 12-15 months. Traditional single-omics studies have identified critical biomarkers such as IDH mutations, MGMT...

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Identifiers

PMID: 41577209
DOI: 10.1016/j.bbcan.2026.189540

Genes

MGMT
EGFR

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 2 Sept 2026.

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