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Major Histocompatibility Complex Immunogenetic Diversity Differs Substantially Across Sea Turtle Species and Genomic Regions.

Genome biology and evolution - 31 Jan 2026

Martin Katherine R, Adkins Jamie L, Chea Vipheaviny, Sarkis Christine M, Phillips Katrina F, Forsman Anna M, Seney Erin E, Komoroske Lisa M, Mansfield Kate L, Savage Anna E

Abstract excerpt

Major histocompatibility complex (MHC) immune loci illustrate how natural selection shapes functional genetic diversity in wild populations. Balancing selection favors high MHC diversity within individuals and populations that persists beyond speciation, leading to shared allelic lineages among taxa. However, some vertebrates show markedly lower allelic diversity and even the loss of entire MHC gene classes....

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Alleles
Evolution, Molecular
Genes, MHC Class II
Genome
Major Histocompatibility Complex

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Selection, Genetic

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PMID: 41575191
DOI: 10.1093/gbe/evag008
PMCID: PMC12891914

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 1 Sept 2026.

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