Article
Evolution of MHC class I genes in the endangered loggerhead sea turtle (Caretta caretta) revealed by 454 amplicon sequencing.
BMC evolutionary biology - 30 Apr 2013
Stiebens Victor A, Merino Sonia E, Chain Frédéric J J, Eizaguirre Christophe
Abstract excerpt
BACKGROUND: In evolutionary and conservation biology, parasitism is often highlighted as a major selective pressure. To fight against parasites and pathogens, genetic diversity of the immune genes of the major histocompatibility complex (MHC) are particularly important. However, the extensive degree of polymorphism observed in these genes makes it difficult to conduct thorough population screenings. METHODS: We...
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