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Combining Whole-Genome Sequencing and Multimodel Phenotyping To Identify Genetic Predictors of Salmonella Virulence.

mSphere - 10 Jun 2020

Crouse Alanna, Schramm Catherine, Emond-Rheault Jean-Guillaume, Herod Adrian, Kerhoas Maud, Rohde John, Gruenheid Samantha, Kukavica-Ibrulj Irena, Boyle Brian, Greenwood Celia M T, Goodridge Lawrence D, Garduno Rafael, Levesque Roger C, Malo Danielle, Daigle France

Abstract excerpt

Salmonella comprises more than 2,600 serovars. Very few environmental and uncommon serovars have been characterized for their potential role in virulence and human infections. A complementary in vitro and in vivo systematic high-throughput analysis of virulence was used to elucidate the association between genetic and phenotypic variations across Salmonella isolates. The goal was to develop a strategy for the...

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Identifiers

PMID: 32522778
DOI: 10.1128/mSphere.00293-20
PMCID: PMC7289705

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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