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Article

Circulating Lipid Peroxides Associate with More Aggressive Tumor Phenotypes and Increased Risks of Recurrence and Mortality in Breast Cancer Patients.

Medical sciences (Basel, Switzerland) - 16 Jan 2026

Orrutéa Julia Fernandes Gois, Matos Rafaela Oliveira, Pinto João Paulo Araújo, Cechinel André Cherubini, Koizumi Bruna Yukie, Paz Rafael Gomes, Almeida Rafaella Frederico, da Silva Janaína Carla, Fagundes Tatiane Renata, Rech Daniel, Welter Wendt Guilherme, Panis Carolina

Abstract excerpt

Background/Objectives: Breast cancer is the most common neoplasm among women and remains the leading cause of cancer-related mortality in the female population worldwide. Tumor cells exist within a highly oxidative microenvironment, which promotes the formation of substantial amounts of lipid peroxides. However, the clinical significance of circulating lipid peroxides in breast cancer is still not well...

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Identifiers

PMID: 41562933
DOI: 10.3390/medsci14010043
PMCID: PMC12821480

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