Article
TMB-related immune gene PAEP influences clear cell renal cell carcinoma progression and prognosis.
European journal of medical research - 17 Jan 2026
Yang Jie, Wu Guoliang, Wu Qian, Hu Xinming, Peng Zechun, Zhang Dan, He Shuming
Abstract excerpt
BACKGROUND: Clear cell renal cell carcinoma (ccRCC) is a prevalent and aggressive form of kidney cancer with a poor prognosis. The tumor mutational burden (TMB) has been a subject of considerable interest in various cancer studies. However, the relationship between TMB and ccRCC has been inadequately explored. This study aimed to elucidate the role of TMB-related immune genes in ccRCC and the underlying molecular...
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