Identification of significant SNPs and the quantification of correlation using genomic informational field theory (GIFT).

Abstract excerpt

Given data on genotypes and phenotypes from a sample population, we show how ordering the data by phenotype and analysing the information contained in the corresponding list of genotypes can identify those SNPs which have a significant correlation with phenotype. We derive formulae for p-values to quantify the significance of each SNP, and show how to analyse the correlations between different SNPs. As well as...

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