Article
GIFT: new method for the genetic analysis of small gene effects involving small sample sizes.
Physical biology - 3 Nov 2022
Rauch Cyril, Kyratzi Panagiota, Blott Sarah, Bray Sian, Wattis Jonathan
Abstract excerpt
Small gene effects involved in complex/omnigenic traits remain costly to analyse using current genome-wide association studies (GWAS) because of the number of individuals required to return meaningful association(s), a.k.a. study power. Inspired by field theory in physics, we provide a different method called genomic informational field theory (GIFT). In contrast to GWAS, GIFT assumes that the phenotype is...
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