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Article

Rethinking DeepVariant: Efficient Neural Architectures for Intelligent Variant Calling.

International journal of molecular sciences - 4 Jan 2026

Gurianova Anastasiia, Pestruilova Anastasiia, Beliaeva Aleksandra, Kasianov Artem, Mikhailova Liudmila, Guguchkin Egor, Karpulevich Evgeny

Abstract excerpt

DeepVariant has revolutionized the field of genetic variant identification by reframing variant detection as an image classification problem. However, despite its wide adoption in bioinformatics workflows, the tool continues to evolve mainly through the expansion of training datasets, while its core neural network architecture-Inception V3-has remained unchanged. In this study, we revisited the DeepVariant design...

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Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

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Identifiers

PMID: 41516386
DOI: 10.3390/ijms27010513
PMCID: PMC12786509

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 8 Sept 2026.

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