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Article

Genetic evidence for causal associations of thrombohemostasis and anticoagulant drug targets with miscarriage.

International journal of gynaecology and obstetrics: the official organ of the International Federation of Gynaecology and Obstetrics - 1 Jul 2026

Zhang Qinyi, Yu Sihui, Wu Hao, Zhang Jiawen

Abstract excerpt

OBJECTIVE: The causal relevance of thrombohemostatic factors and anticoagulant drug targets to miscarriage remains unclear. This study aims to systematically evaluate their potential causal effects on miscarriage phenotypes using Mendelian randomization (MR) analysis. METHODS: We conducted a multidimensional MR study leveraging summary-level genome-wide association study (GWAS) data from individuals of European...

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Abortion, Habitual
Abortion, Spontaneous
Anticoagulants
Aspirin
Hemostasis

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Mendelian Randomization Analysis

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Identifiers

PMID: 41510583
DOI: 10.1002/ijgo.70792

Genes

FGF2

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 1 Sept 2026.

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