Article
ALIFE2 study: low-molecular-weight heparin for women with recurrent miscarriage and inherited thrombophilia--study protocol for a randomized controlled trial.
Trials - 7 May 2015
de Jong Paulien G, Quenby Siobhan, Bloemenkamp Kitty W M, Braams-Lisman Babette A M, de Bruin Jan Peter, Coomarasamy Arri, David Michele, DeSancho Maria T, van der Heijden Olivier W H, Hoek Annemieke, Hutten Barbara A, Jochmans Kristin, Koks Carolien A M, Kuchenbecker Walter K M, Mol Ben Willem J, Torrance Helen L, Scheepers Hubertina C J, Stephenson Mary D, Verhoeve Harold R, Visser Jantien, de Vries Johanna I P, Goddijn Mariëtte, Middeldorp Saskia
Abstract excerpt
BACKGROUND: A large number of studies have shown an association between inherited thrombophilia and recurrent miscarriage. It has been hypothesized that anticoagulant therapy might reduce the number of miscarriages and stillbirth in these women. In the absence of randomized controlled trials evaluating the efficacy of anticoagulant therapy in women with inherited thrombophilia and recurrent miscarriage, a...
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