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Development of indirect immunofluorescence assay for TCID50 measurement of grass carp reovirus genotype II without cytopathic effect onto cells.

Microbial pathogenesis - 1 Jan 2018

Wang Qing, Xie Hualiang, Zeng Weiwei, Wang Linchuan, Liu Chun, Wu Jiexing, Wang Yingying, Li Yingying, Bergmann Sven M

Abstract excerpt

Grass carp reovirus (GCRV) caused severe hemorrhagic disease with significant losses of fingerling and yearling grass carp, Cyenopharyngodon idellus, in southeast Asian. It was first isolated in 1983 in China, and clade analysis of the different GCRV isolates indicates there are at least three different genotypes I, II, and III. In recent years, GCRV genotype II has been determined as a dominant virus type which...

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PMID: 29180293
DOI: 10.1016/j.micpath.2017.11.042

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