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Article

Is chronic low back pain related to sleep disturbances? A self-organizing maps for unsupervised machine learning-based patient phenotyping.

The spine journal : official journal of the North American Spine Society - 1 May 2026

Petrucci Giorgia, Russo Simone, Russo Fabrizio, Vadalà Gianluca, Marchetti Anna, Piredda Michela, Iavicoli Sergio, De Marinis Maria Grazia, Papalia Rocco, Denaro Vincenzo

Abstract excerpt

BACKGROUND CONTEXT: Chronic low back pain (CLBP) is a multifactorial condition and a leading cause of disability worldwide. Among the various contributors to symptom persistence, sleep quality has emerged as a critical yet underexplored factor. Evidence suggests a bidirectional relationship between poor sleep and pain intensity, disability, and psychological distress in individuals with CLBP. PURPOSE: To explore...

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Identifiers

PMID: 41500389
DOI: 10.1016/j.spinee.2026.01.007

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026.

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