Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

High-throughput detection of bovine leukocyte antigen (BoLA)-DRB3 alleles associated with resistance to bovine leukemia virus using a rapid allele-specific PCR assay.

The Journal of veterinary medical science - 1 Mar 2026

Nagai Rin, Ou Yao, Onda Tomoyuki, Noguchi Tatsuo, Kobayashi Tomoko

Abstract excerpt

Bovine leukemia virus (BLV) is the causative agent of enzootic bovine leukosis (EBL), a common neoplastic disease in cattle. Since animals with high BLV proviral load (PVL) pose a greater transmission risk, identifying cattle with low PVL is crucial for herd management. Certain bovine leukocyte antigen (BoLA)-DRB3 alleles- DRB3*009:02, DRB3*014:01:01, and DRB3*002:01-are strongly associated with low PVL in...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Alleles
Share to Cattle

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Disease Resistance

Share to Enzootic Bovine Leukosis

Share to Histocompatibility Antigens Class II

Share to Leukemia Virus, Bovine

Share to Polymerase Chain Reaction

Share to Sensitivity and Specificity

Source

Open in PubMed Open full text

Identifiers

PMID: 41485944
DOI: 10.1292/jvms.25-0429
PMCID: PMC13000438

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 3 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

High-throughput detection of bovine leukocyte antigen (BoLA)-DRB3 alleles associated with resistance to bovine leukemia virus using a rapid allele-specific PCR assay.PMID 41485944Read ↗

Identification of cattle carrying alleles associated with resistance and susceptibility to the Bovine Leukemia Virus progression by real-time PCR.Semantic proximity Read ↗

First Identification of BoLA-DRB3 Alleles Associated with Differential Susceptibility to Bovine Leukemia Virus Infection and Proviral Load in Chinese Holstein Cattle.Semantic proximity Read ↗

BoLA-DRB3 alleles influence proviral load and peripheral blood lymphocyte distribution in bovine leukaemia virus-infected cattle.Semantic proximity Read ↗

Cattle with the BoLA class II DRB3*0902 allele have significantly lower bovine leukemia proviral loads.Semantic proximity Read ↗

A survey of bovine leukemia virus resistant bovine leukocyte antigen (BoLA)-DRB3*009:02 allele-carrying Japanese Black cattle in two prefectures in Japan.Semantic proximity Read ↗

Association between BoLA-DRB3 polymorphism and bovine leukemia virus proviral load in Vietnamese Holstein Friesian cattle.Semantic proximity Read ↗

BoLA-DRB3 Polymorphism is Associated with Differential Susceptibility to Bovine Leukemia Virus-Induced Lymphoma and Proviral Load.Semantic proximity Read ↗

Identification of bovine leukocyte antigen class II haplotypes associated with variations in bovine leukemia virus proviral load in Japanese Black cattle.Semantic proximity Read ↗

A pooled testing system to rapidly identify cattle carrying the elite controller BoLA-DRB3*009:02 haplotype against bovine leukemia virus infection.Semantic proximity Read ↗

Identification of BoLA-DRB3.2 alleles in Korean native cattle (Hanwoo) and Holstein populations using a next generation sequencer.Semantic proximity Read ↗

Bovine major histocompatibility complex (BoLA) heterozygote advantage against the outcome of bovine leukemia virus infection.Semantic proximity Read ↗

Antibody response against three widespread bovine viruses is not impaired in Holstein cattle carrying bovine leukocyte antigen DRB3.2 alleles associated with bovine leukemia virus resistance.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.