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BoLA-DRB3 alleles influence proviral load and peripheral blood lymphocyte distribution in bovine leukaemia virus-infected cattle.

The Veterinary record - 14 Dec 2024

Kobayashi Kenichiro, Katakura Yuki, Ito Yui, Kato Masaki, Goto Yoshiaki, Nakajima Hiromi

Abstract excerpt

BACKGROUND: Bovine leukaemia virus (BLV)-infected Holstein cattle carrying certain bovine leukocyte antigen (BoLA)-DRB3 alleles were previously shown to be resistant to BLV provirus multiplication, while those carrying other alleles were susceptible. This study aimed to determine whether the BoLA-DRB3 alleles carried by BLV-infected cattle could predict proviral load (PVL) and peripheral blood lymphocyte (PBL)...

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Enzootic Bovine Leukosis
Histocompatibility Antigens Class I
Histocompatibility Antigens Class II
Leukemia Virus, Bovine
Lymphocyte Count

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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PMID: 39660663
DOI: 10.1002/vetr.4909

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