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BoLA-DRB3 Polymorphism is Associated with Differential Susceptibility to Bovine Leukemia Virus-Induced Lymphoma and Proviral Load.

Viruses - 22 Mar 2020

Lo Chieh-Wen, Borjigin Liushiqi, Saito Susumu, Fukunaga Koya, Saitou Etsuko, Okazaki Katsunori, Mizutani Tetsuya, Wada Satoshi, Takeshima Shin-Nosuke, Aida Yoko

Abstract excerpt

Bovine leukemia virus (BLV) is the causative agent of enzootic bovine leucosis. However, less than 5% of BLV-infected cattle will develop lymphoma, suggesting that, in addition to viral infection, host genetic polymorphisms might play a role in disease susceptibility. Bovine leukocyte antigen (BoLA)-DRB3 is a highly polymorphic gene associated with BLV proviral load (PVL) susceptibility. Due to the fact that PVL...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Identifiers

PMID: 32235771
DOI: 10.3390/v12030352
PMCID: PMC7150773

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BoLA-DRB3 Polymorphism is Associated with Differential Susceptibility to Bovine Leukemia Virus-Induced Lymphoma and Proviral Load.PMID 32235771Read ↗

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