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Article

Molecular mechanisms underlying early functional divergence in snake venom inferred from the genomes of two pitviper lineages.

BMC biology - 29 Dec 2025

Mason Andrew J, Nachtigall Pedro G, Rokyta Darin R, Parkinson Christopher L, Grazziotin Felipe G, Junqueira-de-Azevedo Inácio L M, Gibbs H Lisle

Abstract excerpt

BACKGROUND: The molecular mechanisms that underlie adaptive divergence in complex traits can be assessed in traits like animal venoms where variation in gene sequence and expression levels can be directly linked to functional divergence in phenotypes. We used novel metrics for measuring functional divergence based on amino acid variation to assess the impact of coding sequence evolution, gene duplication and...

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Identifiers

PMID: 41466268
DOI: 10.1186/s12915-025-02465-8
PMCID: PMC12752072

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