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Article

Auditory genotype-phenotype correlation of patients with variants in STRC.

Scientific reports - 29 Dec 2025

Cheon Tae Uk, Joo Sun Young, Kim Sung Huhn, Choi Jae Young, Won Dongju, Gee Heon Yung, Jung Jinsei

Abstract excerpt

Pathogenic variants in the STRC gene are among the most common causes of autosomal recessive non-syndromic hearing loss, particularly in cases with mild-to-moderate sensorineural hearing loss (SNHL). Despite its prevalence, the clinical phenotype and natural history of STRC-related SNHL remain undercharacterized due to diagnostic challenges posed by a highly homologous pseudogene, pSTRC. This study included 23...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

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Identifiers

PMID: 41461707
DOI: 10.1038/s41598-025-28499-0
PMCID: PMC12749329

Genes

STRC
CATSPER2

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026.

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