Article
STRC Gene Mutations, Mainly Large Deletions, are a Very Important Cause of Early-Onset Hereditary Hearing Loss in the Czech Population.
Genetic testing and molecular biomarkers - 1 Feb 2018
Marková Simona Poisson, Brožková Dana Šafka, Laššuthová Petra, Mészárosová Anna, Krůtová Marcela, Neupauerová Jana, Rašková Dagmar, Trková Marie, Staněk David, Seeman Pavel
Abstract excerpt
INTRODUCTION: Hearing loss (HL) is the most common sensory deficit in humans. HL is an extremely heterogeneous condition presenting most frequently as a nonsyndromic (NS) condition inherited in an autosomal recessive (AR) pattern, termed DFNB. Mutations affecting the STRC gene cause DFNB type 16. Various types of mutations within the STRC gene have been reported from the U.S. and German populations, but no...
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