Article
Exploring the association and mediation between educational attainment and intracerebral hemorrhage: an integrated Mendelian randomization and global burden of disease analysis.
Neurosurgical review - 26 Dec 2025
Li Qi, Shen Yingjie, Wang Yaolou, Li Yanxi, Zhang Haopeng, Meng Xiangyi, Rong Yiwei, Fan Zhaoxin, Wang Huan, Li Xina, Liang Hongsheng
Abstract excerpt
Intracerebral hemorrhage (ICH) significantly threatens human health, and educational attainment (EA) may influence the burden of ICH. We aim to explore the relationship between EA levels and ICH by Mendelian randomization (MR) and Global Burden of Disease (GBD). We conducted bidirectional univariate MR (UVMR) analyses to evaluate the causal relationship between EA levels and ICH, and multivariate MR (MVMR)...
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