Article
SynSeg: A synthetic data-driven approach for robust subcellular structure segmentation.
The Journal of cell biology - 2 Mar 2026
Guo Zhengyang, Wang Zi, Chen Zihan, Xu Kaiming, Chai Yongping, Ke Jingyi, Huang Jingwen, Ye Yuqi, Wang Hui, Zhang Jinxiang, Ou Guangshuo
Abstract excerpt
Accurate subcellular segmentation is crucial for understanding cellular processes, but traditional methods struggle with noise and complex structures. Convolutional neural networks improve accuracy but require large, time-consuming, and biased manually annotated datasets. We developed SynSeg, a pipeline generating synthetic training data for a U-Net model to segment subcellular structures, eliminating manual...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.
