Reduced Ejection Fraction in Elite Endurance Athletes: Clinical and Genetic Overlap With Dilated Cardiomyopathy.

doi:10.1161/CIRCULATIONAHA.122.063777

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Article

Reduced Ejection Fraction in Elite Endurance Athletes: Clinical and Genetic Overlap With Dilated Cardiomyopathy.

Circulation - 30 Apr 2024

Claessen Guido, De Bosscher Ruben, Janssens Kristel, Young Paul, Dausin Christophe, Claeys Mathias, Claus Piet, Goetschalckx Kaatje, Bogaert Jan, Mitchell Amy M, Flannery Michael D, Elliott Adrian D, Yu Chenglong, Ghekiere Olivier, Robyns Tomas, Van De Heyning Caroline M, Sanders Prashanthan, Kalman Jonathan M, Ohanian Monique, Soka Magdalena, Rath Emma, Giannoulatou Eleni, Johnson Renee, Lacaze Paul, Herbots Lieven, Willems Rik, Fatkin Diane, Heidbuchel Hein, La Gerche André

Abstract excerpt

BACKGROUND: Exercise-induced cardiac remodeling can be profound, resulting in clinical overlap with dilated cardiomyopathy, yet the significance of reduced ejection fraction (EF) in athletes is unclear. The aim is to assess the prevalence, clinical consequences, and genetic predisposition of reduced EF in athletes. METHODS: Young endurance athletes were recruited from elite training programs and underwent...

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PMID: 38109351
DOI: 10.1161/CIRCULATIONAHA.122.063777
PMCID: PMC11062611

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